Paul Tofts - Publications
(updated February 26th 2007)
This is a list of publications in journals and books. It does not include conference proceedings, invited lectures, or unpublished reports, which are all available separately.
Up to date information can be obtained from the internet:
www.pubmed.org search for tofts ps (145 hits) or tofts p (153 hits).
ISI web of Science 198 hits; over 4000 citations
Many of the publications can be downloaded as pdf files; links are available from html and word versions of this CV (but not the pdf version).
A: Books, chapters
A1. Clinical 31-P NMR spectroscopy.
EB Cady, DT Delpy, PS Tofts. in 'Physical principles and clinical applications of Nuclear Magnetic Resonance' ed RA Lerski. pub Institute of Physical Scientists in Medicine (1985)
A2. Tissue localization in surface coil nuclear magnetic resonance (NMR) spectroscopy.
PS Tofts. In: Neonatal physiological measurements pp363‑372. Ed P.Rolfe. Butterworths, London (1986).
A3. Cerebral metabolism in newborn infants studied by phosphorus nuclear magnetic resonance spectroscopy.
PL Hope, AM de L Costello, EB Cady, DT Delpy, PS Tofts, A Chu, EOR Reynolds, DR Wilkie. In: Neonatal physiological measurements pp382‑389. Ed P.Rolfe. Butterworths, London (1986).
A4. Networks and image handling.
Proceedings of a conference organised by the Institute of Physical Scientists in Medicine (IPSM), Cardiff 1986.
Paul S Tofts and R Cranage (eds). Published by IPSM, London. 1987.
A5. The MRI measurement of NMR and physiological parameters in tissue to study disease process.
PS Tofts, DAG Wicks and GJ Barker. XIth international conference on Information Processing in Medical Imaging pp313-326 (ed. D.Ortendahl,; Wiley-Liss, New York 1990).
A6. Changing activity in MS lesions: an MRI study.
AG Kermode, PS Tofts, AJ Thompson, P Rudge, DG MacManus, BE Kendall, IF Moseley, DPE Kingsley and WI McDonald.
In: Recent Advances in multiple sclerosis therapy. eds Gonsette RE and Delmotte P. pp43-46. International congress series, Amsterdam, Elsevier (1989).
A7. Quantitative information on bones and muscles from the EMI CT5005 whole body scanner.
PS Tofts, SR Grindrod. Information Processing in Medical Imaging INSERM 88:121‑134 (Paris 1980).
A8. Functional imaging, magnetisation transfer and relaxation times.
PS Tofts. In: Nato advanced workshop on MR techniques and epilepsy (ed SD Shorvon, DR Fish, GM Bydder and H Stefan); New York; Plenum press 1994; p275-279. (1994)
A9. The significance of T2 changes in the hippocampus.
PS Tofts. In: Nato advanced workshop on MR techniques
and epilepsy (eds SD Shorvon, DR Fish, GM Bydder and H Stefan); New York;
Plenum press 1994; p71-73. (1994)
A10. Welcome Witness seminar: making the body transparent: the impact of Nuclear Magnetic Resonance and Magnetic Resonance Imaging. Participant and contributor at a meeting held at the Wellcome Institute 2 July 1996. In Welcome Witnesses to Twentieth Century Medicine vol 2 1998.
A11. Tofts,P.S. (2003). Concepts: measurement and MR. Chapter 1 in Tofts,P.S. (ed.) Quantitative MRI of the brain: measuring changes caused by disease. Chichester: John Wiley, 3-15. ISBN: 0-470-84721-2
A12. Tofts,P.S. (2003). The measurement process: MR data collection and image analysis. Chapter 2 in Tofts,P.S. (ed.) Quantitative MRI of the brain: measuring changes caused by disease. Chichester: John Wiley, 17-54. ISBN: 0-470-84721-2
A13. Tofts,P.S. (2003). QA: quality assurance, accuracy, precision and phantoms. Chapter 3 in Tofts,P.S. (ed.) Quantitative MRI of the brain: measuring changes caused by disease. Chichester: John Wiley, 55-81. ISBN: 0-470-84721-2
A14. Tofts,P.S. (2003). PD: proton density of tissue water. Chapter 4 in Tofts,P.S. (ed.) Quantitative MRI of the brain: measuring changes caused by disease. Chichester: John Wiley, 85-109. ISBN: 0-470-84721-2
A15. Tofts,P.S., Steens,S.C.A., van Buchem,M.A. (2003). MT: magnetization transfer. Chapter 8 in Tofts,P.S. (ed.) Quantitative MRI of the brain: measuring changes caused by disease. Chichester: John Wiley, 257-298. ISBN: 0-470-84721-2
A16. Tofts,P.S., Waldman,A.D. (2003). Spectroscopy: [1]H metabolite concentrations. Chapter 9 in Tofts,P.S. (ed.) Quantitative MRI of the brain: measuring changes caused by disease. Chichester: John Wiley, 299-339. ISBN: 0-470-84721-2
A17. Tofts,P.S., Davies,G.R., Dehmeshki,J. (2003). Histograms: measuring subtle diffuse disease. Chapter 18 in Tofts,P.S. (ed.) Quantitative MRI of the brain: measuring changes caused by disease. Chichester: John Wiley, 581-610. ISBN: 0-470-84721-2
A18. Tofts,P.S. (2003). The future of qMR: conclusions and speculation. Chapter 19 in Tofts,P.S. (ed.) Quantitative MRI of the brain: measuring changes caused by disease. Chichester: John Wiley, 613-617. ISBN: 0-470-84721-2
B: Peer reviewed articles
1975-86
B1. A continuous wave NMR millidegree thermometer.
MG Richards, PS Tofts, PR Turner. Cryogenics 13: 182‑185 (1973).
B2. Frequency dependence of T1 for He‑3 in solid He‑4.
MG Richards, JH Smith, PS Tofts, WJ Mullin. Physics Review Letters 34:1545‑1547 (1975).
B3. The motion of He‑3 impurity in solid He‑4.
MG Richards, JH Smith, PS Tofts, WJ Mullin. Soviet Journal of Low Temperature Physics 1: 275‑277 (1975).
B4. NMR measurements on dilute solutions of He‑3 in solid He‑4.
MG Richards, J Pope, PS Tofts, JH Smith. Journal of Low Temperature Physics 24: 1‑24 (1976).
B5. Statistical limitations in computed tomography.
JC Gore, PS Tofts. Phys Med Biol 23:1176‑1182 (1978).
B6. Transit times and ratio of moments.
PS Tofts, AD Linney. Phys Med Biol 24:455 (1979).
B6. A multicentre comparison of computer assisted image processing and display methods.
AS Houston, PF Sharp, PS Tofts, BL Diffey. Phys Med Biol 24:547‑558 (1979).
B8. Absolute values of attenuation coefficient in computed tomography. (letter)
JC Gore, PS Tofts. Phys Med Biol 24:828‑830 (1979).
B9. Some sources of artefact in computed tomography.
PS Tofts, JC Gore. Phys Med Biol 25:117‑127 (1980).
B10. Definitions of effective energy in computed tomography.
PS Tofts. Phys Med Biol 26:313‑317 (1981).
B11. Investigation of human skeletal muscle structure and composition by X-ray computerised tomography.
Sue Grindrod, Paul Tofts, Richard Edwards. European Journal of Clinical Investigation 13:465‑468 (1983).
B12. Non-invasive investigation of cerebral metabolism in newborn infants by phosphorus nuclear magnetic resonance spectroscopy.
EB Cady, AM de L Costello, MJ Dawson, DT Delpy, PL Hope, EOR Reynolds, PS Tofts, DR Wilkie. Lancet (i) 1059‑1062 (1983).
B13. Size and composition of the calf and quadriceps muscles in Duchenne muscular dystrophy.
DA Jones, JM Round, RHT Edwards, SR Grindrod, PS Tofts. Journal of the Neurological Sciences 60:307‑322 (1983).
B14. Cerebral energy metabolism studied with phosphorus NMR spectroscopy in normal and birth-asphyxiated infants.
PL Hope, AM de L Costello, EB Cady, DT Delpy, PS Tofts, A Chu, PA Hamilton, EOR Reynolds, DR Wilkie. Lancet (ii) 366‑370 (1984).
B15. Surface coil NMR spectroscopy of brain.
PS Tofts, EB Cady, DT Delpy, AM de L Costello, PL Hope, EOR Reynolds, DR Wilkie, SJ Gould, D Edwards. Lancet (i) 459 (1984).
B16. Changes in brain phosphorus metabolites during the post natal development of the rat.
Paul Tofts and Susan Wray. J Physiol 359:417‑429 (1985)
B17. Direct in-vivo measurement of absolute metabolite concentrations using 31P nuclear magnetic resonance.
S Wray and PS Tofts. Biochem Biophys Acta 886:399‑405 (1986).
B18. Magnetic resonance imaging of experimental cerebral oedema.
D Barnes, WI McDonald, PS Tofts, G Johnson, DN Landon. J Neurol Neurosurg Psychiatry 49:1341‑1347 (1986).
1987
B19. A SAFE (Saturate AFter the Echo) sequence to eliminate an artefact in the measurement of T2 in partially saturated NMR systems.
Paul S Tofts and G Johnson. Phys Med Biol 32:1345‑1353 (1987).
B20. Accuracy and precision in the measurement of relaxation times from nuclear magnetic resonance images.
G Johnson, IEC Ormerod, D Barnes, PS Tofts, D MacManus. Brit J Radiol 60:143‑153 (1987).
B21. Accuracy and precision in the measurement of relaxation times in NMR imaging.
G Johnson, IEC Ormerod, D Barnes, PS Tofts, D MacManus. Brit J Radiol 60:1041-1042 (1987). Letter.
B22. Edited 31-P brain spectra using Maximum Entropy data processing.
ML Waller and Paul S Tofts. Magn Reson Med 4:385‑392 (1987).
B23. Measurement of NMR relaxation times using the minimum number of scans.
G Johnson, IEC Ormerod, PS Tofts, D Barnes, EPGH du Boulay. Stockholm 1986. Acta Radiologica supplement 369:496‑499 (1987)
B24. Quantitative nuclear magnetic resonance imaging: characterisation of experimental cerebral oedema.
D Barnes, WI McDonald, G Johnson, PS Tofts, DN Landon. J Neurol Neurosurg Psychiatry 50:125‑133 (1987).
B25. STIR sequences in NMR imaging of the optic nerve.
G Johnson, DH Miller, D MacManus, PS Tofts, D Barnes, EPGH du Boulay, WI McDonald. Neuroradiology 29:238‑245 (1987).
B26. The NMR signal decay characteristics of cerebral oedema.
D Barnes, EPGH du Boulay, WI McDonald, G Johnson, PS Tofts. Stockholm 1986. Acta Radiologica supplement 369:503‑506 (1987).
B27. The role of NMR imaging in the assessment of multiple sclerosis and 'isolated' neurological lesions: a quantitative study.
IEC Ormerod, DH Miller, WI McDonald, EPGH du Boulay, P Rudge, BE Kendell, IF Moseley, G Johnson, AM Halliday, F Scarivilli, PS Tofts, KJ Zilka. Brain 110:1579‑1616 (1987)
1988
B28. A critical assessment of methods of measuring metabolite concentrations by NMR spectroscopy.
PS Tofts and S Wray. NMR in Biomedicine 1:1‑10 (1988).
B29. Non-invasive measurement of molar concentrations of 31-P metabolites in-vivo, using surface coil spectroscopy.
Paul S Tofts and Susan Wray. Magn Reson Med 6:84‑86 (1988).
B30. The noninvasive measurement of absolute metabolite concentrations in-vivo using surface coil NMR spectroscopy.
Paul S Tofts. J Magn Reson 80:84-95 (1988).
B31. Multiline chemical-shift (MULCH) imaging.
G Johnson and PS Tofts. Magn Reson Med 6:107‑115 (1988).
B32. Ring artefacts in x-ray computed tomography.
RW Cranage and PS Tofts. Brit J Radiol 61:529 (1988).
B33. The early lesion of multiple sclerosis.
AG Kermode, PS Tofts, DG MacManus, BE Kendall, DPE Kingsley, IF Moseley, EPGH du Boulay, WI McDonald. Lancet (ii) 1203-1204 (1988).
B34. 19-F imaging of cerebral blood oxygenation in experimental middle cerebral artery occlusion: preliminary results.
D Eidelberg, G Johnson, PS Tofts, J Dobbin, HA Crockard, D Plummer. J Cerebral blood flow and metabolism 8:276‑281 (1988).
B35. 19-F NMR imaging of blood oxygenation in the brain.
D Eidelberg, G Johnson, D Barnes, PS Tofts, D Delpy, D Plummer and WI McDonald. Magn Reson Med 6:344‑352 (1988).
1989
B36. Blood brain permeability measured in multiple sclerosis using labelled DTPA with PET, CT and MRI.
PS Tofts, AG Kermode. Journal of Neurology, Neurosurgery and Psychiatry 52:1019-1020 (1989).
B37. Precise relaxation time measurements of normal appearing white matter in inflammatory central nervous system disease.
DH Miller, G Johnson, PS Tofts, D Macmanus and WI McDonald. Magn Reson Med 11:331-336 (1989).
B38. Use of greyscale voxel databases for improved shading and segmentation.
S.R.Arridge, S.R.Grindrod, A.D.Linney, P.S.Tofts and D.Wicks,. Medical Informatics 14:157-171 (1989).
1990
B39. Nasal orientation device to control head movement during CT and MR studies.
PS Tofts, AG Kermode, DG MacManus and WH Robinson. Journal of Computer Assisted Tomography 14:163-164 (1990).
B40. The distribution of induced currents in magnetic stimulation of the brain.
PS Tofts. Physics in Medicine and Biology 35:1119-1128 (1990).
B41. Towards quantitative measurements of relaxation times and other parameters in the brain.
PS Tofts and EPGH du Boulay. Neuroradiology 32:407-415 (1990).
B42. Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis: pathogenetic and clinical implications.
AG Kermode, AJ Thompson, PS Tofts, DG MacManus, BE Kendall, DPE Kingsley, IF Moseley, P Rudge, WI McDonald. Brain 113:1477-1489 (1990).
B43. Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis studied by gadolinium-DTPA and protein markers.
CP Hawkins, PMG Munro, F Mackenzie, J Kesselring, PS Tofts, EPGH du Boulay, DN Landon, WI McDonald. Brain 113:365-378 (1990).
B44. Heterogeneity of blood-brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement.
AG Kermode, PS Tofts, AJ Thompson, DG MacManus, P Rudge, BE Kendall, DPE Kingsley, IF Moseley, EPGH du Boulay and WI McDonald. Neurology 40:229-235 (1990).
B45. Magnetic stimulation of a volume conductor produces a negligible component of induced current perpendicular to the surface.
NM Branston and PS Tofts. J Physiol 423:67P (1990).
B46. Non-invasive measurement of human blood-brain barrier transfer constant using dynamic magnetic resonance imaging.
AG Kermode and PS Tofts. J Physiol 423:42P (1990).
B47. Transcranial magnetic stimulation.
NB Branston and PS Tofts. Neurology 40:1909 (1990). Letter.
1991
B48. Measurement of the Blood-Brain Barrier permeability and leakage space using dynamic MR imaging - 1 Fundamental concepts.
PS Tofts and AG Kermode. Magnetic Resonance in Medicine 17:357-367 (1991).
B49. The measurement of electric field, and the influence of surface charge, in magnetic stimulation.
PS Tofts and NM Branston. Electroencephalography and clinical Neurophysiology 81:238-239 (1991).
B50. Analysis of the distribution of currents induced by a changing magnetic field in a volume conductor. NM Branston and PS Tofts. Phys Med Biol 36:161-168 (1991).
B51. Onset and duration of blood-brain barrier breakdown in multiple sclerosis.
AG Kermode, AJ Thompson, PS Tofts, DG MacManus, S Moore, BE Kendall, DPE Kingsley, IF Moseley, WI McDonald. American Academy of Neurology. Neurology 33:125-126 (1991).
B52. Patterns of blood-brain barrier breakdown in inflammatory demyelination.
CP Hawkins, F MacKenzie, P(S) Tofts, EPGH DuBoulay and WI MacDonald. Brain 114:801-810 (1991).
B53. Sources of T1 variance in normal human white matter.
I Harvey, PS Tofts, JK Morris, DAG Wicks, and MA Ron. Magn Reson Imag 9:53-59 (1991).
B54. The pathophysiology of acute optic neuritis. An association of gadolinium leakage with clinical and electrophysiological deficits. BD Youl, G Turano, DH Miller, AD Towell, DG MacManus, SG Moore, SJ Jones, G Barrett, BE Kendall, IF Moseley, PS Tofts, AM Halliday and WI McDonald. Brain 114:2437-2450 (1991).
1992
B55. Accurate and precise measurement of blood-retinal barrier breakdown using dynamic Gd-DTPA MRI.
BA Berkowitz, PS Tofts, HA Sen, N Ando and E de Juan. Investigative Ophthalmology and Visual Science 33:3500-3506 (1992).
B56. In-vivo T1 values from guinea pig brain depend on body temperature.
BD Youl, CP Hawkins, JK Morris, EPGH DuBoulay and PS Tofts. Magn Reson Med 24:170-173 (1992).
B57. Measurement of Blood Brain Barrier permeability using dynamic Gd-DTPA scanning - a comparison of methods.
HBW Larsson and PS Tofts. Magn Reson Med 24:174-176 (1992).
B58. Semiautomated quality assurance for quantitative magnetic resonance imaging.
G Barker and PS Tofts. Magn Reson Imag 10:585-595 (1992).
B59. Volume measurement of multiple sclerosis lesions with magnetic resonance images.
DAG Wicks, PS Tofts, DH Miller, GH du Boulay, A Feinstein, RP Sacares, I Harvey, R Brenner and WI McDonald. Neuroradiology 34:475-479 (1992).
1993
B60. Ni-DTPA doped agarose gel - a phantom material for Gd-DTPA enhancement measurements.
PS Tofts, B Shuter and JM Pope. Magn Reson Imag 11:125-133 (1993).
B61. Rapid measurement of capillary permeability using the early part of the dynamic Gd-DTPA MRI enhancement curve.
PS Tofts and BA Berkowitz. J Magn Reson (series B) 102:129-136 (1993).
B62. A chemical shift selective inversion recovery sequence for fat-suppressed MRI: theory and experimental validation.
E Kaldoudi, SCR Williams, GJ Barker and PS Tofts. Magn Reson Imag 11:341-355 (1993).
B63. Correction of intensity non-uniformity in magnetic resonance images of any orientation.
DAG Wicks, G Barker, PS Tofts. Magn Reson Imag 11:183-196 (1993).
B64. Database for serial magnetic resonance imaging in multiple sclerosis.
F Barkhof, AJ Thompson, L Kappos, JJP Nauta, T Yousri, I Berry, G Scotti, B Appel, PS Tofts and DH Miller. Neuroradiology 35:362-366 (1993).
B65. Detection of myelin breakdown products by proton magnetic resonance spectroscopy.
CA Davie, CP Hawkins, GJ Barker, A Brennan, PS Tofts, DH Miller, WI McDonald. Lancet (i):630-631 (1993).
B66. Spinal cord MRI using multi-array coils and fast spin echo 1: technical spects and findings in healthy adults.
JW Thorpe, D Kidd, BE Kendall, PS Tofts, GJ Barker, AJ Thompson, DG MacManus, WI McDonald and DH Miller. Neurology 43:2625-2631 (1993).
1994
B67. Correction of nonuniformity in images of the spine and optic nerve from fixed receive-only surface coils at 1.5T.
PS Tofts, GJ Barker, AMK Simmons, D MacManus, J Thorpe, A Gass and DH Miller. J Comput Assist Tomogr 18:997-1003 (1994).
B68. Measurement of capillary permeability from the Gd
enhancement curve - a comparison of bolus and constant infusion injection
methods.
PS Tofts and B Berkowitz. Magnetic Resonance Imaging 12:81-91 (1994).
B69. Standing waves in uniform water phantoms.
PS Tofts. J Magn Reson series B 104:143-147 (1994).
B70. A method for visualisation of MRI partial volume regions - PAIR (PArtial volume sensitised Inversion Recovery Imaging).
A Simmons, GJ Barker, PS Tofts, A Gass and SR Arridge. Magn Reson Imaging 12:821-826 (1994).
B71. Benign and secondary progressive multiple sclerosis: a preliminary quantitative MRI study.
M Filippi, GJ Barker, MA Horsfield, PR Sacares, DG MacManus, AJ Thompson, PS Tofts, WI McDonald, DH Miller. J Neurol 241:246-251 (1994).
B72. Correlation of Magnetisation Transfer Ratio with Clinical Disability in Multiple Sclerosis.
A Gass, GJ Barker, D Kidd, JW Thorpe, D MacManus, A Brennan, PS Tofts, AJ Thompson, WI McDonald and DH Miller. Annals of Neurology 36:62-67 (1994).
B73. Detection of multiple sclerosis by magnetic resonance imaging.
JW Thorpe, GJ Barker, DG MacManus, IF Moseley, PS Tofts, DH Miller. Lancet 344:1235.
B74. Effect of vitreous fluidity on the measurement of blood-retinal barrier permeability using contrast enhanced MRI.
BA Berkowitz, CA Wilson, PS Tofts, RM Peshock. Magn Reson Med 31:61-66 (1994).
B75. Improvements to the quality of MRI cluster analysis.
A Simmons, SR Arridge, GJ Barker, AJ Cluckie, PS Tofts. Magn Reson Imag 12:1191-1204 (1994).
B76. Proton MRS in Huntington's disease.
CA Davie,GJ Barker, N Quinn, PS Tofts, DH Miller. Lancet 343:1580 (1994).
B77. Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions.
CA Davie, CP Hawkins, GJ Barker, A Brennan, PS Tofts, DH Miller, WI McDonald. Brain 117:49-58 (1994).
B78. Short tau inversion recovery fast spin-echo (Fast STIR) imaging of the spinal cord in multiple sclerosis.
JW Thorpe, DG MacManus, BE Kendall, PS Tofts, GJ Barker, WI McDonald and DH Miller. Magn Reson Imag 12:983-989 (1994).
B79. Sources of intensity non-uniformity in spin echo images at 1.5T
A Simmons, PS Tofts, GJ Barker and SR Arridge. Magn Reson Med 32:121-128 (1994).
B80.The role of diffusion in NMR imaging of the CNS.
MA Horsfield, C Davie, PS Tofts and DH Miller. Argomenti di Neurologia 4:84-89 (1994)
1995
B81. MR magnetisation transfer measurements in temporal lobe epilepsy.
PS Tofts, S Sisodiya, GJ Barker, S Webb, D MacManus, D Fish, S Shorvon. Am J NeuroRadiology 16:1862-1863 (1995).
B82. Novel MR image contrast mechanisms in epilepsy.
Paul S Tofts. Magn Reson Imag 13:1099-1106;1995.
B83. Quantitative analysis of dynamic Gd-DTPA enhancement in breast tumours using a permeability model.
PS Tofts B Berkowitz and M Schnall. Magn Reson Med 33:564-568 (1995).
B84. Differentiation of multiple system atrophy from idiopathic Parkinson's disease using proton magnetic resonance spectroscopy.
CA Davie, GK Wenning, GJ Barker, PS Tofts, BE Kendall, N Quinn, WI McDonald, CD Marsden, DH Miller. Annals of Neurology 37:204-210 (1995).
B85. High resolution magnetic resonance imaging of the anterior visual pathway in patients with optic neuropathies using fast spin echo and phased array local coils.
A Gass, GJ Barker, D MacManus, M Sanders, P Riordan-Eva, PS Tofts, J Thorpe, WI McDonald, IF Moseley, DH Miller. J Neurol Neurosurg Psychiatry 58:562-569 (1995).
B86. Magnetisation transfer ratios and transverse magnetisation decay curves in optic neuritis: correlation with clinical findings and electrophysiology.
JW Thorpe, GJ Barker, SJ Jones, I Moseley, N Losseff, DG MacManus, S Webb, C Mortimer, DL Plummer, PS Tofts, WI McDonald and DH Miller. J Neurology Neurosurgery Psychiatry 59:487-492 (1995).
B87. Persistent functional deficit in
multiple sclerosis and autosomal dominant cerebellar ataxia is associated with
axon loss.
CA Davie, GJ Barker, S.Webb, PS Tofts, AJ Thompson, AE Harding, WI McDonald, DH Miller. Brain 118:1583-1592 (1995). (erratum in Brain 119:1415 (1996))
B88. Proton magnetic resonance spectroscopy: an in vivo method of estimating hippocampal neuronal depletion in schizophrenia.
M Maier, MA Ron, GJ Barker, PS Tofts. Psychological Medicine 25:1201-1209 (1995). [erratum Psychological Medicine 26:877 (1996)]
B89. Quantitative assessment of MRI lesion load in monitoring the evolution of multiple sclerosis.
M.Filippi, MA Horsfield, PS Tofts, F Barkhof, AJ Thompson, DH Miller. Brain 118:1601-1612;1995.
B90. The effect of sacrifice on image signal,T1, T2 and T2* in liver, kidney, and brain of the Wistar rat.
B Shuter, PS Tofts and JM Pope. Magn Reson Imag 13:563-574 (1995).
1996
B91. Optimal detection of blood-brain barrier defects with Gd-DTPA MRI - the influences of delayed imaging and optimised repetition time.
PS Tofts. Magn Reson Imag 14:373-380 (1996).
B92. An interleaved sequence for accurate and reproducible clinical measurement of magnetization transfer ratio.
GJ Barker, PS Tofts and A Gass. Magn Reson Imag 14:403-411 (1996)
B93. Apparent diffusion coefficients in benign and secondary progressive multiple sclerosis by nuclear magnetic resonance.
MA Horsfield, M Lai, SL Webb, GJ Barker, PS Tofts, R Turner, P Rudge, DH Miller. Magn Reson Med 36:393-400 (1996).
B94. Lesion volume measurement in multiple sclerosis: how important is accurate repositioning?
ML GawneCain, S.Webb, P(S) Tofts, DH Miller. J Magn Reson Imag 6:705-713 (1996).
B95. Macroscopic and microscopic assessments of disease burden by MRI in multiple sclerosis: relationship to clinical parameters.
C Gasperini, MA Horsfield, JW Thorpe, D Kidd, GJ Barker, PS Tofts, DG MacManus, AJ Thompson, DH Miller, WI McDonald. J Magn Reson Imag 6:580-584 (1996).
B96. Magnetic resonance imaging in epilepsy with a fast FLAIR sequence.
UC Wieshmann, SL Free, AD Everitt, PA Bartlett, GJ Barker, PS Tofts, JS Duncan, SD Shorvon, JM Stevens. J Neurology Neurosurgery and Psychiatry 61:357-361 (1996).
B97. MRI of the optic nerve in benign intracranial hypertension.
A Gass, GJ Barker, P Riordan-Eva, D MacManus, M Sanders, PS Tofts, WI McDonald, IF Moseley, DH Miller. Neuroradiology 38:769-773 (1996).
B98. Quantification of MRI lesion load in multiple
sclerosis: a comparison of three computer-assisted techniques.
Grimaud J, Lai M, Thorpe J, Adeleine P, Wang L, Barker GJ, Plummer DL, Tofts PS, McDonald WI, Miller DH. Magnetic Resonance Imaging 14:495-505 (1996).
B99. Spinal cord atrophy and disability in multiple sclerosis: a new reproducible and sensitive MRI method with potential to monitor disease progression.
Losseff NA, Webb SL, O'Riordan JI, Page R, Wang L, Barker GJ, Tofts PS, McDonald WI, Miller DH, Thompson AJ. Brain 119:701-708 (1996)
B100. The relaxivity of Gd-EOB-DTPA and Gd-DTPA in liver and kidney of the Wistar rat.
B Shuter, PS Tofts, S-C Wang and JM Pope.Magn Reson Imag 14:243-253 (1996).
1997
B101. A low dielectric constant customised phantom design to measure RF coil nonuniformity.
PS Tofts, GJ Barker, TL Dean, H Gallagher, AP Gregory, RN Clarke. Magn Reson Imag 15:(1) 69-75 (1997).
B102. An Oblique Cylinder Contrast-Adjusted (OCCA) phantom to measure the accuracy of brain lesion volume estimation schemes in multiple sclerosis.
PS Tofts, GJ Barker, M Filippi, M Gawne-Cain, M Lai. Magn Reson Imag 15:183-192 (1997).
B103. Modeling tracer kinetics in dynamic Gd-DTPA MR imaging
PS Tofts. J Magnetic Resonance Imaging 7:91-101 (1997).
B104. 1H magnetic resonance spectroscopy of chronic cerebral white matter lesions and normal appearing white matter in multiple sclerosis.
CA Davie, GJ Barker, AJ Thompson, PS Tofts, WI McDonald, DH Miller. J Neurology Neurosurgery and Psychiatry 63:736-742 (1997).
B105. Magnetisation transfer ratio of normal brain white matter: a normative database spanning four decades of life.
NC Silver, GJ Barker, DG MacManus, PS Tofts, DH Miller. J Neurol Neurosurg Psychiatry 62:223-228 (1997).
B106. Serial magnetisation transfer ratios in gadolinium-enhancing lesions in multiple sclerosis.
HM Lai, CA Davie, A Gass, GJ Barker, S Webb, PS Tofts, AJ Thompson, WI McDonald, DH Miller. J Neurol 244:308-311 (1997).
B107. Strategies for optimizing MR imaging techniques aimed at monitoring disease activity in multiple sclerosis trials.
F Barkhof, M Filippi, D Miller, P Tofts, L Kappos, A Thompson. J Neurol 244:76-84 (1997).
B108. The transverse magnetisation decay characteristics of longstanding lesions and normal-appearing white matter in multiple sclerosis.
D Kidd, GJ Barker, PS Tofts, A Gass, AJ Thompson, WI McDonald, DH Miller. J Neurology 244:125-130 (1997).
1998
B109. Standardisation and optimisation of magnetic resonance
techniques for multicentre studies.
PS Tofts. J Neurology Neurosurgery and Psychiatry 1998; 64 (supplement 1):S37-43.
B110. Application of the extremum stack to neurological MRI.
Simmons A, Arridge SR, Tofts PS, Barker GJ. IEEE Trans Med Imaging 1998;17(3):371‑382
B111. A simple method for investigating the effects of non‑uniformity of radiofrequency transmission and radiofrequency reception in MRI.
GJ Barker, A Simmons, SR Arridge, PS Tofts. Brit J Radiology 71:59-67 (1998).
B112. Correction for variations in MRI scanner sensitivity in brain studies with histogram matching
L Wang, HM Lai, GJ Barker, DH Miller, PS Tofts. Magn Reson Med 1998; 39:322-327.
B113. Guidelines for using quantitative measures of brain magnetic resonance imaging abnormalities in monitoring the treatment of multiple sclerosis.
M Filippi, MA Horsfield, HJ Ader, F Barkhof, P Bruzzi, A
Evans, JA Frank, RI Grossman, HF McFarland, P Molyneux, DW Paty, J Simon, PS
Tofts , J Wolinsky, DH Miller. Ann Neurol 1998; 43:499-506.
B114. Precision and reliability for measurement of change in MRI lesion volume in multiple sclerosis: a comparison of two computer assisted techniques.
Molyneux PD, Tofts PS, Fletcher A, Gunn B, Robinson P, Gallagher H, Moseley IF,
Barker GJ, Miller DH. J Neurol Neurosurg Psychiatry 1998 Jul;65(1):42‑7.
B115. Quantitative techniques for lesion load measurement in multiple sclerosis: an assessment of the global thresholdtechnique after non uniformity and histogram matching corrections.
Molyneux PD, Wang L, Lai M, J G, Tofts PS, Moseley IF, H D. Eur J Neurol 1998 5:55‑60.
B116. T1 hypointense lesion load in secondary progressive multiple sclerosis: a comparison of pre versus post contrast loads and of manual versus semi automated threshold techniques for lesion segmentation.
O'Riordan JI, Gawne Cain M, Coles A, Wang L, Compston DA, Tofts P(S), Miller DH. Mult Scler 1998; 4:408‑12.
B117. The effect of section thickness on MR lesion detection and quantification in multiple sclerosis.
Molyneux PD, Tubridy N, Parker GJ, Barker GJ, MacManus DG, Tofts PS, Moseley IF, Miller DH. AJNR Am J Neuroradiol 1998;19:1715‑20.
1999
B118. Estimating kinetic parameters from dynamic contrast-enhanced T1-weighted MRI of a diffusable tracer: standardized quantities and symbols. PS Tofts, G Brix, DL Buckley, JL Evelhoch, E Henderson, M Knopp, HBW Larsson, T-Y Lee, NA Mayr, GJM Parker, RE Port, J Taylor, RM Weisskoff. Journal of Magnetic Resonance Imaging 1999;10:223-232. Review.
B119. A multicenter measurement of magnetization transfer ratio in normal white matter.
I Berry, GJ Barker, F Barkhof, A Campi, V Dousset, JM Franconi,
A Gass, W Schreiber, DH Miller PS Tofts. J Magn Reson Imag 1999;9:441-446.
B120. An in Vivo Evaluation of the Effects of Local Magnetic Susceptibility‑Induced Gradients
on Water Diffusion Measurements in Human Brain.
CA Clark, GJ Barker, PS Tofts. Journal of Magnetic Resonance 1999;141(1):52‑61.
B121. Correlation of magnetic resonance imaging parameters with clinical disability in multiple sclerosis: a preliminary study.
Grimaud J, Barker GJ, Wang L, Lai M, MacManus DG, Webb SL, Thompson AJ, McDonald WI, Tofts PS, Miller DH. J Neurol 1999; 246:961-967.
B122. Does the extent of axonal loss and demyelination from chronic lesions in multiple sclerosis correlate with the clinical subgroup?
CA Davie, NC Silver, GJ Barker, PS Tofts, AJ Thompson, WI McDonald, DH Miller. Journal of Neurology, Neurosurgery and Psychiatry 1999; 67:710-715.
B123. Hippocampal Layers on High Resolution Magnetic Resonance Images: Real or Imaginary?
UC Wieshmann, MR Symms, JP Mottershead, DG MacManus, GJ Barker, PS Tofts,
T Revesz, JM Stevens, SD Shorvon. J Anatomy 1999;195 (pt 1):131-135
B124. Magnetic resonance diffusion imaging of the human cervical spinal cord in vivo.
CA Clark, GJ Barker, PS Tofts. Magn Reson Med 1999; 41:1269‑1273.
B125. MR Imaging of Tumor Microcirculation: Promise for the New Millenium.
Taylor, JS, Tofts PS, Port R, Evelhoch JL, Knopp M, Reddick WE, Runge VM, Mayr N. Journal of Magnetic Resonance Imaging 1999;10:903-907.
B126. Pharmacokinetic analysis of neoplasms using contrast-enhanced dynamic MR imaging.
GJM Parker, PS Tofts. Topics in Magnetic Resonance Imaging. 1999;10:130-142. Review.
|
|
|
B127. Texture analysis of spinal cord pathology in multiple sclerosis
JM Mathias, PS Tofts, NA Losseff. Magn Reson Med 1999; 42:929-935.
2000
B128. Test liquids for quantitative MRI measurements of self-diffusion coefficient in-vivo.
PS Tofts, D Lloyd, CA Clark, GJ Barker, GJM Parker, P McConville, C Baldock, JM Pope. Magn Reson Med 2000; 43:368‑374. Download pdf
B129. Improved reduction of motion artifacts in diffusion imaging using navigator echoes and velocity compensation. Clark CA, Barker GJ, Tofts PS. Journal of Magnetic Resonance 2000; 142:358-363.
|
B130. Magnetization
transfer imaging. van Buchem MA, Tofts PS. Neuroimaging Clin N Am.
2000;10:771-788 |
|
B131. Variations in T1 and T2 relaxation times of normal appearing white matter and lesions in multiple sclerosis.
Stevenson VL, Parker GJM, Barker GJ, Birnie K, Tofts PS, Miller DH, Thompson AJ. Journal of Neurological Sciences 2000; 178:81‑87
B132. Volunteer studies replacing animal experiments in brain research.
Langley G, Harding G, Hawkins P, Jones A, Newman C, Swithenby S, Thompson D, Tofts P(S), Walsh V. ATLA 28:315-331 (2000).
2001
B133. Accurate multislice gradient echo T1 measurement in the presence of non-ideal RF pulse shape and RF field non-uniformity.
Parker GJM, Barker GJ, Tofts PS. Magn Reson Med 2001; 45:838-845
B134. Analysis of MTR histograms in multiple sclerosis using principal components and multiple discriminant analysis.
Dehmeshki J, Ruto AC, Arridge S, Silver NC, Miller DH, Tofts PS. Magn Reson Med 2001;46:600-609
B135. Magnetisation transfer ratio histogram analysis of primary progressive and other multiple sclerosis subgroups.
Dehmeshki J, Silver NC, Leary SM, Tofts PS, Thompson AJ, Miller DH. Journal of the Neurological Sciences 2001; 185:11-17.
B136. Measuring the Human Retinal Oxygenation Response to a Hyperoxic Challenge using MRI: Eliminating blinking artifacts and demonstrating proof of concept.
Berkowitz BA, McDonald C, Ito Y, Tofts PS, Latif Z, Gross J. Magn Reson Med 2001; 46:412-416.
B137. Quantitative contrast-enhanced magnetic resonance imaging to evaluate blood-brain barrier integrity in multiple sclerosis: a preliminary study.
Silver NC, Tofts PS, Symms MR, Barker GJ, Thompson AJ, Miller DH. Multiple Sclerosis 2001; 7:75-82
B138. Simple methods for the correction of T2 maps of phantoms.
Lepage M, Tofts PS, Back SAJ, Jayasekera PM, Baldock C. Magn Reson Med 2001; 46:1123‑9.
|
2002
B145. Another
approach to protons with constricted mobility in white matter: pilot studies
using wideline and high-resolution NMR spectroscopy. Ramani A, Aliev
AE, Barker GJ, Tofts PS. Magn Reson Imaging 2003; 21:1039-43.
B146. High field
MRI correlates of myelin content and axonal density in multiple sclerosis--a
post-mortem study of the spinal cord. Mottershead JP,
Schmierer K, Clemence M, Thornton JS, Scaravilli F, Barker GJ, Tofts PS,
Newcombe J, Cuzner ML, Ordidge RJ, McDonald WI, Miller DH. J Neurol 2003;
250:1293-301
B151. Removing
spikes caused by quantization noise from high-resolution histograms. Tozer DJ, Tofts PS. Magn Reson Med 2003; 50:649-53. Download pdf. 2004 |
|
||||||||||||||||||||||||||||||||
|
|
|
||||||||||||||||||||||||||||||||
B152. Abnormalities of cerebral
perfusion in multiple sclerosis.
Rashid W, Parkes LM, Ingle GT, Chard DT, Toosy AT, Altmann DR,
Symms MR, Tofts PS, Thompson AJ,
Miller DH. J Neurol Neurosurg Psychiatry 2004; 75:1288-93
B153. Diffusion
tensor imaging of early relapsing-remitting multiple sclerosis with histogram
analysis using automated segmentation and brain volume correction.
Rashid W, Hadjiprocopis A, Griffin CM,
Chard DT, Davies GR, Barker GJ, Tofts PS, Thompson AJ, Miller DH. Mult
Scler 2004; 10:9-15.
B154. Estimation of the
macromolecular proton fraction and bound pool T2 in multiple sclerosis.
Davies GR, Tozer DJ, Cercignani M, Ramani A, Dalton CM,
Thompson AJ, Barker GJ, Tofts PS, Miller
DH. Mult Scler 2004; 10:607-13. Download pdf.
B155. Measuring blood volume and
vascular transfer constant from dynamic T(2)*-weighted contrast-enhanced MRI.
Johnson G, Wetzel SG, Cha S,
Babb J, Tofts PS. Magn Reson Med
2004;51:961-8.
B156. Normal cerebral perfusion
measurements using arterial spin labeling: reproducibility, stability, and age
and gender effects.
Parkes LM, Rashid W, Chard
DT, Tofts PS. Magn Reson Med 2004; 51:736-43.
B157. Reproducibility of
brain ADC histograms.
Steens SC, Admiraal-Behloul
F, Schaap JA, Hoogenraad FG, Wheeler-Kingshott CA, le Cessie S, Tofts PS, van Buchem MA.Eur Radiol
2004;14:425-30.
2005
B158. The assessment of antiangiogenic and antivascular
therapies in early-stage clinical trials using magnetic resonance imaging:
issues and recommendations.
Leach
MO, Brindle KM, Evelhoch JL, Griffiths JR, Horsman MR, Jackson A, Jayson GC,
Judson IR, Knopp MV, Maxwell RJ, McIntyre D, Padhani AR, Price P, Rathbone R,
Rustin GJ, Tofts PS, Tozer GM,
Vennart W, Waterton JC, Williams SR, Workman P; Pharmacodynamic/Pharmacokinetic
Technologies Advisory Committee, Drug Development Office, Cancer Research UK. Br J Cancer 2005; 92:1599-610. Download pdf.
B159. Assessment and
correction of B1-induced errors in magnetization transfer ratio measurements.
Ropele S, Filippi M,
Valsasina P, Korteweg T, Barkhof F, Tofts
PS, Samson R, Miller DH, Fazekas F. Magn Reson Med 2005; 53:134-40
B160. Correlation of
apparent myelin measures obtained in multiple sclerosis patients and controls
from magnetization transfer and multicompartmental T2 analysis.
Tozer DJ, Davies
GR, Altmann DR, Miller DH, Tofts PS.
Magn Reson Med 2005; 53:1415-22.
B161. Dynamic contrast
enhanced MRI in patients with diabetic macular edema: initial results
Trick GL, Liggett J, Levy J,
Adamsons I, Edwards P, Desai U, Tofts PS,
Berkowitz BA. Exp Eye Res 2005; 81:97-102.
B162. Increasing
normal-appearing grey and white matter magnetisation transfer ratio abnormality
in early relapsing-remitting multiple sclerosis.
Davies GR, Altmann DR, Hadjiprocopis A, Rashid W, Chard DT, Griffin
CM, Tofts PS, Barker GJ, Kapoor R,
Thompson AJ, Miller DH. J Neurol 2005; 252:1037-44
B163. Object strength--an accurate
measure for small objects that is insensitive to partial volume effects.
Tofts
PS, Silver NC, Barker GJ, Gass A. MAGMA
2005; 18:162-9. Download pdf
B164. A standardised method
for measuring magnetisation transfer ratio on MR imagers from different
manufacturers--the EuroMT sequence.
Barker GJ, Schreiber WG,
Gass A, Ranjeva JP, Campi A, van Waesberghe JH, Franconi JM, Watt HC, Tofts PS. MAGMA 2005; 18:76-80. Download pdf
B165. Three-dimensional
quantitative magnetisation transfer imaging of the human brain.
Cercignani M, Symms MR, Schmierer K, Boulby PA, Tozer DJ, Ron M, Tofts PS, Barker GJ. Neuroimage 2005;
27:436-41. Download pdf
B166. Unbiased segmentation
of diffusion-weighted magnetic resonance images of the brain using iterative
clustering. Hadjiprocopis A, Rashid W, Tofts PS. Magn Reson Imag 2005; 23:877-85.
2006
B167. 1H-MRS internal thermometry in test-objects (phantoms) to within 0.1 K for quality assurance in long-term quantitative MR studies.
Samson RS, Thornton JS, McLean MA, Williams SC, Tofts PS. NMR Biomed. 2006;19:560-5.
B168. Principal component and linear discriminant analysis of T1 histograms of white and grey matter in multiple sclerosis.
Tozer DJ, Davies GR, Altmann DR, Miller DH, Tofts PS. Magn Reson Imaging. 2006; 24:793-800. Download pdf
B169. Quantitative analysis of whole-tumor Gd enhancement histograms predicts malignant transformation in low-grade gliomas.
Tofts PS, Benton CE, Weil RS, Tozer DJ, Altmann DR, Jager HR, Waldman AD, Rees JH. J Magn Reson Imaging. 2007; 25:208-214
B170. A simple correction for B1 field errors in magnetization transfer ratio measurements.
Samson RS, Wheeler-Kingshott CA, Symms MR, Tozer DJ, Tofts PS. Magn Reson Imag 2006; 24:255-63
2007
B172a. Apparent diffusion coefficient histograms may predict low-grade glioma subtype.
Tozer DJ , Jager HR , Danchaivijitr N , Benton CE , Tofts PS , Rees JH , Waldman AD . NMR Biomed. 2007; 20:49-57.
B172b. Diffusion tensor imaging of post mortem multiple sclerosis brain.
Schmierer K , Wheeler-Kingshott CA, Boulby PA, Scaravilli F, Altmann DR, Barker GJ, Tofts PS, Miller DH. Neuroimage. 2006 Dec 16; [Epub ahead of print]
(NB 2007
B reference numbers are temporary)